• Weil Nutrition Corner
  • Meet Dr. Weil
  • Origins
  • Healthy Aging
  • Marketplace
  • Podcasts
  • Accessibility
  • Subscribe
Dr. Weil Logo Dr. Weil Logo Weil™ Andrew Weil, M.D.
  • Health & Wellness
    Health & Wellness
    Body, Mind & Spirit
    • Addiction
    • Allergy & Asthma
    • Autoimmune Disorders
    • Back Pain
    • Bone & Joint
    • Cancer
    • Colds & Flu
    • Dental & Oral
    • Diabetes
    • Disease & Disorders
    • Ears, Nose, & Throat
    • Feet
    • Gastrointestinal
    • Hair, Skin, & Nails
    • Headache
    • Heart
    • Insects & Parasites
    • Liver & Kidney
    • Mental Health
    • Pregnancy & Fertility
    • Respiratory
    • Sexual Health
    • Sleep Issues
    • Stress & Anxiety
    • Vision
    Balanced Living
    • Exercise & Fitness
    • Gardening
    • Healthy Home
    • Healthy Living
    • Meditation & Inspiration
    • Meet Dr. Weil
    • Pets & Pet Care
    • Technology
    • Wellness Therapies
    Health Centers
    • Aging Gracefully
    • Children
    • Condition Care Guide
    • Men
    • Women
  • Diet & Nutrition
    Diet & Nutrition
    Anti-Inflammatory Diet & Pyramid
    Cooking & Cookware
    Diets & Weight Loss
    Food Safety
    Nutrition
    Recipes
  • Vitamins, Supplements & Herbs
    Vitamins, Supplements & Herbs
    Herbs
    Supplements & Remedies
    Vitamins
  • Ask Dr. Weil
  • Blogs
    Blogs
    Bulletins
    Health Tips
    Spontaneous Happiness
  • Mushrooms
  • Sleep
Press "Enter" to search
Dr. Weil Logo Weil™ Andrew Weil, M.D.
  • Health & Wellness
    Health & Wellness
    Body, Mind & Spirit
    • Addiction
    • Allergy & Asthma
    • Autoimmune Disorders
    • Back Pain
    • Bone & Joint
    • Cancer
    • Colds & Flu
    • Dental & Oral
    • Diabetes
    • Disease & Disorders
    • Ears, Nose, & Throat
    • Feet
    • Gastrointestinal
    • Hair, Skin, & Nails
    • Headache
    • Heart
    • Insects & Parasites
    • Liver & Kidney
    • Mental Health
    • Pregnancy & Fertility
    • Respiratory
    • Sexual Health
    • Sleep Issues
    • Stress & Anxiety
    • Vision
    Balanced Living
    • Exercise & Fitness
    • Gardening
    • Healthy Home
    • Healthy Living
    • Meditation & Inspiration
    • Meet Dr. Weil
    • Pets & Pet Care
    • Technology
    • Wellness Therapies
    Health Centers
    • Aging Gracefully
    • Children
    • Condition Care Guide
    • Men
    • Women
  • Diet & Nutrition
    Diet & Nutrition
    Anti-Inflammatory Diet & Pyramid
    Cooking & Cookware
    Diets & Weight Loss
    Food Safety
    Nutrition
    Recipes
  • Vitamins, Supplements & Herbs
    Vitamins, Supplements & Herbs
    Herbs
    Supplements & Remedies
    Vitamins
  • Ask Dr. Weil
  • Blogs
    Blogs
    Bulletins
    Health Tips
    Spontaneous Happiness
  • Mushrooms
  • Sleep
  • Weil Nutrition Corner
  • Meet Dr. Weil
  • Origins
  • Healthy Aging
  • Marketplace
  • Podcasts
  • Accessibility
  1. Home
  2. Health & Wellness
  3. Health Centers
  4. Aging Gracefully

Maintaining Your Brain?

Is it true that physical activity and a high-fiber diet can prevent dementia and slow the brain from shrinking as we age?

Andrew Weil, M.D. | June 4, 2021

Maintaining Your Brain? | Aging Gracefully | Andrew Weil, M.D.
1 min

You may be referring to information stemming from a study of natives in the Bolivian Amazon, the Tsimane, who reportedly experience less brain atrophy with age than Americans and Europeans. The Tsimane are believed to have the world’s healthiest arteries, and their brains are said to age 70 percent more slowly than ours do.

A study published in 2017 found that these people also have extraordinarily healthy hearts in older age and the lowest prevalence of coronary atherosclerosis of any known population.

Researchers believe that the health of the Tsimane is likely related to their pre-industrial subsistence lifestyle. They eat vegetables, fish, and some lean meat and are extremely physically active as hunters, fishers, and foragers.

After studying the Tsmaine more recently, researcher Andrei Irimia, Ph.D., of the University of Southern California concluded that these natives “have provided us with an amazing natural experiment on the potentially detrimental effects of modern lifestyle on our health.” In a study published this year (2021), he added that the latest findings suggest that brain atrophy may be slowed substantially by adopting the same lifestyle practices associated with a very low risk of heart disease.

The USC researchers used brain scans conducted in the closest town to the Tsimanes homeland where CT scanning equipment was available. The scans enabled the researchers to determine that shrinkage in Tsimane brain volume between middle age and old age is 70 percent less than it is among Western populations. Brain atrophy is correlated with cognitive impairment, functional decline and dementia.

According to study author Hillard Kaplan, Ph.D., a professor of health economics and anthropology at Chapman University who has studied the Tsimane for nearly two decades, “The Tsimane can serve as a baseline for healthy brain aging.” He added that “our sedentary lifestyle and diet rich in sugars and fats may be accelerating the loss of brain tissue with age and making us more vulnerable to diseases such as Alzheimer’s.”

Andrew Weil, M.D.

Source:
Andrei Irimia and Hillard Kaplan et al “The indigenous South American Tsimane exhibit relatively modest decrease in brain volume with age despite high systemic inflammation.” The Journals of Gerontology: May 26, 2021, DOI: 10.1093/gerona/glab138

Read more tips, recipes, and insights on a wide variety of topics from Dr. Weil here.

House Cleaning & Your Brain | Weekly Bulletins | Andrew Weil, M.D.
Bulletins

House Cleaning & Your Brain

How The Mediterranean Diet Works | Diet | Andrew Weil M.D.
Diets & Weight Loss

Mediterranean Diet And Brain Health?

Advertisement
Related Weil Products

Follow Dr. Weil On Instagram!

Looking for more health and wellness tips from Dr. Weil! Get a peek into his daily life, his Rhodesian Ridgeback dogs, his garden, and his wellness travels? Follow along on Instagram and see what he’s up to! You can also find him on Facebook, Tik Tok and Twitter.
Dr. Weil's Photos
Dr. Weil on Healthy Aging

Start Your 14-Day Free Trial

Free Newsletters

Stay Connected With Dr. Weil

Anti-Inflammatory Diet

Follow Dr. Weil’s Food Pyramid

Get Dr Weils Newsletter Updates

Exclusive Lifestyle, Nutrition & Health Advice

Dr. Weil's FREE health living advice delivered to you!

By clicking "Subscribe," you agree to the DrWeil.com Terms and Conditions and Privacy Policy. You also agree to receive emails from DrWeil.com, and you may opt out of DrWeil.com subscriptions at any time.

Trending Now

Two Ways to Protect the Brain - Dr. Weil
Aging Gracefully

2 Ways To Protect The Brain

foods that promote healthy vision
Aging Gracefully

3 Foods That Promote Healthy Vision

3 Ways To Prepare For Lifelong Health | Andrew Weil, M.D.
Aging Gracefully

3 Ways To Prepare For Lifelong Health

4 Changes For Life Satisfaction
Aging Gracefully

4 Changes For Life Satisfaction

Dr. Weil Logo Weil™ Andrew Weil, M.D.
Dr. Weil's Signature

Exclusive Lifestyle, Nutrition & Health Advice

  • About Us
  • Press Information
  • Advertising
  • Contact Us
  • Terms of Use
  • Privacy Policy
  • Accessibility

Terms of Use | Privacy Policy

Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Any third party offering or advertising on this website does not constitute an endorsement by Andrew Weil, M.D. or Healthy Lifestyle Brands.

© Copyright 2025 Healthy Lifestyle Brands, LLC. All rights reserved. Reproduction in whole or in part without permission is prohibited. www.drweil.com