Antacids are medications that are usually used to treat indigestion or reflux. They may work by neutralizing stomach acid or preventing the production of stomach acid. Indigestion is clear sign that you are offending your stomach either by eating too much, eating too often, eating the wrong foods, consuming irritating substances and drugs, or letting anxiety and stress interfere with digestion. Consuming antacids is not the solution. Changes in your diet, lifestyle and stress management are much better long-term solutions than antacids.