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Medical investigation has shown that an important contributor in the aging process is the decay of the mitochondria - the organelles within the cell that convert amino acids, fatty acids and sugars into energy. Studies performed by the Berkeley research team and others have demonstrated that as we age, the efficiency of the mitochondria diminishes, as does their quantity per cell. The effect? A body operating at one-half to one-fourth the energy it had at youth. The brain is perhaps the most important organ affected by aging, since it consumes more energy than any other organ of the body. An energy deficit in the brain and central nervous system affects the activities of organs throughout the body as well as mental acuity and mood.*

The ingredients in Weil Juvenon Healthy Aging Support are based on substances that are produced naturally in the body in sufficient levels to maintain health in youth, but may not be present in the same quantities as we age.* The product is a patented composition of mitochondrial metabolites that has been shown in laboratory experiments to help preserve and maintain mitochondrial function as cells age,* by:

• Maintaining the membrane potential*
• Promoting metabolism and cell function*
• Enhancing anti-oxidative protection*
• Promoting cellular health*

Help protect and maintain healthy cells - buy Weil Juvenon Healthy Aging Support today.* Join our Monthly Convenience Program to continually promote a healthier, more energetic body. Money Back Guarantee.

Stimulation of Mitochondrial Function*

Weil Juvenon Healthy Aging Support contains a compound known to stimulate the synthesis of cardiolipin, a key component of the mitochondria. Cardiolipin is a phospholipid that is necessary, along with specific transport enzymes, to maintain the potential and overall integrity of the mitochondrial membrane. The membrane potential is the result of the separation of charge between the inner and outer surface of the membrane, a process that requires energy-driven pumps to move charged particles against a gradient. A young, healthy mitochondrion (one containing sufficient cardiolipin) has a maximum membrane potential and therefore maximum energy producing potential. The compounded ingredients in Weil Juvenon also activate the transport of high-energy dietary-derived products into the mitochondria, where they are transformed into a specific chemical form of energy (ATP).* This captured energy is used to run the cellular machinery for such activities as muscle contraction and neurotransmission.*

Promotion of Cellular Antioxidants

In addition to the constituents that promote optimal energy production in cells, the patented composition contains substances to protect cellular integrity. Scientists have demonstrated the production of cell-damaging oxidants in body tissues under normal physiological conditions. The bulk of these oxidants are controlled or neutralized by cellular antioxidants, but a portion of these highly reactive substances invariably escapes this defense and survives to contribute to the aging process. Furthermore, as a consequence of accumulated damage, our antioxidant defense becomes less effective as the body ages, diminishing the efficiency of defense-building enzymes.

To address this situation Weil Juvenon has added an antioxidant compound containing two important properties. First, working in concert with the compound described above, it too plays a critical role in the conversion of food into energy, and secondly, it affords protection to the cell from oxidants, including the highly reactive substances known as free radicals. Free radicals are chemical by-products, produced during the conversion of food to form energy. They are extremely toxic to the cell as they oxidize and distort its vital components. This constituent of the Juvenon product is an amphipathic substance, meaning it is both water and lipid soluble, and can therefore penetrate and protect lipid containing cell membranes as well as water soluble cell components. Another important characteristic of this multiple function compound is its capacity to be regenerated to an active form, within the cell, after reacting with and neutralizing an oxidant. It can literally protect all of the cellular components from oxidants. In addition to being an antioxidant, it helps maintain a high membrane potential by working in synergy with other cellular antioxidants, including vitamins C and E, as well as glutathione, to keep them fully charged for maximum cellular protection from oxidants.*

It is perhaps the most potent of the natural cellular antioxidants, as it is very easily oxidized due to its low redox potential.* This makes it a more attractive substance for the radical to attack, sparing the vital cell structures from destruction. Listed below are some of the specific beneficial effects observed at the cellular level:

• Maintaining a high membrane potential*
• Maintaining optimum metabolic activity*
• Increasing energy production*
• Reducing the level of free radicals*

Theory of Aging

The free radical or mitochondrial theory of aging has received increasing recognition during the last 20 years. A basic tenet of this theory is that the fundamental changes associated with the aging process are the cumulative result of the reactive oxygen species (ROS) which are normal by-products of aerobic life. Physical exercise is an integral part of daily life. Prominent physiologic changes, which occur during exercise, include: an increased metabolic rate, an enhanced rate of mitochondrial respiration, and oxidative phosphorylation.

During maximal muscular contraction in men, it has been estimated that oxygen consumption can be as much as 100 times the resting level for local muscle fibers and 20 times for the whole body. This high rate of oxygen flux may lead to increased electron "leakage" found at the resting condition and poses an oxidative stress to the mitochondria and other critical cellular organelles [1]. As we age, the skeletal muscle is under increasing oxidative stress, as evidenced by higher levels of lipid peroxidation and antioxidant defense in aged muscles.

The theory states that mitochondria are the major source of toxic oxidants, which are capable of reacting with and destroying cell constituents and which accumulate with age. The consequence of this destructive activity over time is an inefficient cell and a body we recognize as aged. The gradual loss of energy with age is paralleled by a decrease in number of mitochondria per cell, as well as the health and energy-producing efficiency of those remaining mitochondria.

Learn more about Weil Juvenon Healthy Aging Support* - read some commonly asked questions on the Q&A page.

Help protect and maintain healthy cells - buy Weil Juvenon Healthy Aging Support today.* Join our Monthly Convenience Program to continually promote a healthier, more energetic body.* Money back guarantee.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

1 - Jenkins, RR and Goldfarb, A. Introduction: oxidant stress, aging, and exercise. Med Sci Sports Exerc. 1993 Feb;2(2) :210-2

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